Sage Therapeutics
Sage Therapeutics Headquarters Location
Cambridge, MA
Sage Therapeutics Photos
About Sage Therapeutics
Sage Therapeutics is a biopharmaceutical company committed to developing novel therapies with the potential to transform the lives of people with debilitating disorders of the brain. We are pursuing new pathways with the goal of improving brain health and our depression, neurology and neuropsychiatry franchise programs aim to change how brain disorders are thought about and treated. Our mission is to make medicines that matter so people can get better, sooner.
The human brain is the most complex organ of the human body. It is made up of an integrated network of approximately 100 billion nerve cells called neurons, connected in complex electrical circuits to communicate. Brain health and function depend on the interaction of these circuits. Navigating these complex circuits is a challenge, but a welcome opportunity for the teams at Sage as we seek to develop novel medicines.
Sage is a place where unconventional thinking to solve problems with new ideas is welcome – and where unconventional thinkers can imagine what’s possible and do big.
Read our Community Guidelines: http://bit.ly/2tFyAoj
#ThisIsSageThe human brain is the most complex organ of the human body. It is made up of an integrated network of approximately 100 billion nerve cells called neurons, connected in complex electrical circuits to communicate. Brain health and function depend on the interaction of these circuits. Navigating these complex circuits is a challenge, but a welcome opportunity for the teams at Sage as we seek to develop novel medicines.
Sage is a place where unconventional thinking to solve problems with new ideas is welcome – and where unconventional thinkers can imagine what’s possible and do big.
Read our Community Guidelines: http://bit.ly/2tFyAoj
We’ve worked hard to create an energetic, engaging culture where ideas, creativity, and speed are valued. Our people are motivated to work hard, have fun, and deliver on their promises. Each day we are excited by and proud of the work that we do to develop new medicines to treat CNS disorders.
A Peek InsideWe are a team fearless in our pursuit to discover and develop life-changing therapies for patients living with central nervous system (CNS) disorders. We are passionate about what we do, and when it comes to a great work environment, we deliver - excellent benefits, a rewarding career, and a fun place to work.
Our ScienceThe human brain is a complex and integrated network. Navigating this intricate circuitry presents a challenge to developing innovative treatments needed for brain disorders. We seek to develop meaningfully differentiated medicines by rethinking disorders of the central nervous system (CNS).
We take a focused, practical and deliberate approach to drug development in pursuit of novel and differentiated medicines for people with CNS disorders. We’re studying the potential of our novel drug candidates to modulate brain activity. Our goal is to develop products that may address gaps in available treatment options. We use a translational research strategy to explore the action of our compounds, and their therapeutic potential for restoring normal CNS function.
GABA AND NMDA RECEPTORS
The human brain is a network of billions of nerve cells, connected in complex electrical circuits to communicate. Brain function and mental health depend on these circuits. Neural regulatory pathways, like GABA and NMDA receptors systems, manage the flow of information. Dysfunction in the GABA and NMDA receptor signaling pathways are implicated in a broad range of CNS disorders.
GABA is an inhibitory neurotransmitter found throughout the brain. It binds to its receptors to put the brakes on nerve activity and calm the brain. When out of balance, this pathway potentially plays a role in various CNS disorders, including several neurological and mood disorders.
Activated NMDA receptors increase signaling between nerve cells, and play a critical role in stabilizing neural networks. This excitatory receptor system is also implicated in many psychiatric and neurological CNS disorders. We are helping to pioneer research to understand the role of NMDA receptors in disease.
Sage has designed a large library of novel, proprietary compounds that can specifically modulate GABA or NMDA receptor activity. We’re studying our development compounds for their therapeutic potential in restoring normal CNS function. Our goal is to develop products that may address gaps in available treatment options for CNS disorders.
Sage Core ValuesWe take a focused, practical and deliberate approach to drug development in pursuit of novel and differentiated medicines for people with CNS disorders. We’re studying the potential of our novel drug candidates to modulate brain activity. Our goal is to develop products that may address gaps in available treatment options. We use a translational research strategy to explore the action of our compounds, and their therapeutic potential for restoring normal CNS function.
GABA AND NMDA RECEPTORS
The human brain is a network of billions of nerve cells, connected in complex electrical circuits to communicate. Brain function and mental health depend on these circuits. Neural regulatory pathways, like GABA and NMDA receptors systems, manage the flow of information. Dysfunction in the GABA and NMDA receptor signaling pathways are implicated in a broad range of CNS disorders.
GABA is an inhibitory neurotransmitter found throughout the brain. It binds to its receptors to put the brakes on nerve activity and calm the brain. When out of balance, this pathway potentially plays a role in various CNS disorders, including several neurological and mood disorders.
Activated NMDA receptors increase signaling between nerve cells, and play a critical role in stabilizing neural networks. This excitatory receptor system is also implicated in many psychiatric and neurological CNS disorders. We are helping to pioneer research to understand the role of NMDA receptors in disease.
Sage has designed a large library of novel, proprietary compounds that can specifically modulate GABA or NMDA receptor activity. We’re studying our development compounds for their therapeutic potential in restoring normal CNS function. Our goal is to develop products that may address gaps in available treatment options for CNS disorders.
Put People First
Believe our mission will make a difference in the lives of patients.
Keep our patients and their families’ best interest in mind.
We value our people and our teams.
Care about each other, what we do, and our community.
Be Accountable
Be responsible to ourselves, our teams, our company, and our stakeholders.
Results and relationships matter.
Possess a solution-oriented mindset and execute with a sense of urgency.
Make wise decisions in the face of ambiguity.
Communicate respectfully and openly.
Do Big
Create new opportunities and challenge the conventional wisdom.
Think beyond boundaries.
Be fearless in our pursuits.
Take smart risks always in the best interest of our patients.
Collaborate and foster innovation.
Grow Through Learning & Change
Understand our industry, strategy, market, and stakeholders.
Learn from our successes and challenges.
Motivate and empower each other to reach our full potential.
Anticipate and embrace change.
Work Fun
Celebrate.
Be passionate about what we do.
Embed excitement and positive energy in our everyday work.
Sagean Stories: Erin part 1Believe our mission will make a difference in the lives of patients.
Keep our patients and their families’ best interest in mind.
We value our people and our teams.
Care about each other, what we do, and our community.
Be Accountable
Be responsible to ourselves, our teams, our company, and our stakeholders.
Results and relationships matter.
Possess a solution-oriented mindset and execute with a sense of urgency.
Make wise decisions in the face of ambiguity.
Communicate respectfully and openly.
Do Big
Create new opportunities and challenge the conventional wisdom.
Think beyond boundaries.
Be fearless in our pursuits.
Take smart risks always in the best interest of our patients.
Collaborate and foster innovation.
Grow Through Learning & Change
Understand our industry, strategy, market, and stakeholders.
Learn from our successes and challenges.
Motivate and empower each other to reach our full potential.
Anticipate and embrace change.
Work Fun
Celebrate.
Be passionate about what we do.
Embed excitement and positive energy in our everyday work.
Erin talks about the importance of truly thinking differently how we challenge ourselves on a daily basis. Learn more about Sage at http://bit.ly/2u8aqTU
Number of Employees in Sage Therapeutics
501 to 1,000
Sage Therapeutics Revenue
Hidden by employer
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